Digital health technologies are an essential tool for alleviating the strain on global healthcare systems. Yet, there are no guarantees that the technologies will deliver the hoped-for efficiency gains. To realize the promise of digital health, companies need to build robust, collaborative ecosystems that pool the full range of expertise needed to innovate, scale, and sustain digital health solutions.
The term “digital health” covers a wide range of technologies that can make healthcare more efficient, optimize the diagnosis, treatment, and management of conditions, and ultimately enable patients to live longer, healthier lives. A Reuters webinar brought together digital health experts to discuss how pharma companies and other stakeholders can work together to scale the technology. The stakes are high.
“There are a lot of companies that have tried and failed over the last 10 to 15 years, but it has to succeed because otherwise healthcare systems will simply break,” Richard Cassidy, SVP and Head of the RX+ Business Accelerator at Astellas, said. “We have to figure out a way to work together to make it happen.”
How to Build Digital Health Partnerships
The wide range of capabilities needed to develop, deploy, and scale digital health technologies make partnerships essential. Pharma companies have scientific knowledge and experience generating clinical evidence, but may lack expertise possessed by startups that specialize in digital health.
Nipun Jain, Head of Innovation Hubs & Partnerships for International at AstraZeneca, said “innovation does not happen in isolation; it requires all stakeholders to come together.” While the webinar revealed broad agreement on the centrality of partnerships to digital health success, it also showed the challenges of bringing together companies that may have very different cultures and objectives.
“Aligning on a common goal, on objectives, and on the right ways of doing things is often a challenge in creating these ecosystems,” Jain said. “It needs to start with the right objective. Getting that objective defined is the first challenge.”
Cassidy added that all parties in a collaboration need to understand what a project is trying to achieve and be able to link that back to their own business goals. Adrian Gheorghiu, Sustainability-Innovation Coordination Lead, WP 4 Industry Lead, Gravitate Health & Director, Digital Global Client Partner, Pfizer, made the case for putting the patient at the heart of partnerships.
“Digital health partnerships have to be organized around the patient’s well-being and health outcomes, not the other way around,” Gheorghiu said. “You need to frame the problem. What do I want to solve? Make a problem statement and then organize the value chain around that.”
Why Scaling Tools is Critical to Success
Technologies need to scale to have the sort of healthcare-saving impact envisaged by Cassidy. Haider Allegory, General Partner at Allegory Capital, said pharma companies can suffer from a “death by pilot effect” that causes many projects to end before making an impact. Speaking from his perspective as an investor, Allegory encouraged companies to think hard about how to scale initiatives.
“We say any engagement program that you build that has a million patients is going to have an impact. If you have a patient engagement program that has 3,000 patients doing a retrospective clinical trial, that is great for those 3,000 patients. My question will be how do we get to 1 million?” Allegory said. “That is usually where we get stuck in the conversation.”
Jain discussed how AstraZeneca is tackling the scalability challenge. Acknowledging that something that is easy to do for thousands of people can be hard to do at scale, Jain said that AstraZeneca has created a network of 17 innovation hubs to launch solutions that have impacted millions of patients globally. Jain’s successes include using AI to identify the risk of lung cancer in routine chest x-rays in 25 countries.
“We are able to do that at scale, but we are only able to do that at scale when it's rooted in science, it's rooted in evidence,” Jain said. “We are partnering with the right ecosystems and then we are creating value in terms of supporting clinicians to triage their patients and not replace them.”
What AI Means for Digital Health
Jain’s example points to the potential for AI to enable the deployment of digital health interventions at global scale. Roberta Pandolfi, Analytics Innovation strategist, Global Clinical Development & Operations at Boehringer Ingelheim, discussed the state of AI and how to maximize the impact of the technology.
“AI digitalization is here to stay. It’s not going to be the future; actually, it’s already the present,” Pandolfi said. “The most important thing in order to be effective is to use AI and digitalization with coaches and especially to educate our people. It's not magic. It's something that takes some time and effort.”
Cassidy flagged specific training and education requirements for large language models such as ChatGPT. The models enable people without specialist knowledge to interrogate complex datasets. Putting that power in the hands of more people creates opportunities to improve efficiency but, Cassidy said, it also creates risks. People need to learn how to ask models questions to get reliable results, Cassidy said.
Gheorghiu shared the other panelists’ enthusiasm for AI and belief in the need to proceed with caution, explaining that the technology “needs to be really well managed” to avoid increasing the legal, ethical, and compliance risks that companies face.
Conclusion
The digital health sector is at the leading edge of technology but its success hinges on people, not a new device, software, or other high-tech breakthrough. Human connections will inform whether companies with very distinct cultures and objectives can find the common ground needed to forge partnerships that make a virtue of their differences. Equally, it is people who will shape and be shaped by AI
As Pandolfi put it, it is “the human being that has to be there, has to be properly educated, and has to be a part of a big orchestration.” The orchestration of tech startups, pharma companies, patients, and other stakeholders is key to realizing the potential of digital health. Unifying the groups behind common goals will be demanding, but the webinar revealed widespread commitment to rising to the challenge.
Contributors
Roberta Pandolfi, Analytics Innovation strategist - Global Clinical Development & Operations, Boehringer Ingelheim
Richard Cassidy, SVP and Head of the RX+ Business Accelerator, Astellas
Nipun Jain, Head of Innovation Hubs & Partnerships for International, AstraZeneca
Haider Allegory, General Partner, Allegory Capital
Adrian Gheorghiu, Sustainability-Innovation Coordination Lead, WP 4 Industry Lead, Gravitate Health & Director, Digital Global Client Partner, Pfizer
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